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Drugs targeting B-Cells in autoimmune diseases edited by Xavier Bosch, Manuel Ramos-Casals, Munther A Khamashta - Basel Springer International Publishing 2014 - 1 recurso en línea (XI, 292 p.) 3 ilustraciones, 2 ilustraciones en color - Milestones in Drug Therapy 2296-6056 .

Historic Outline of the Development of Drugs Targeting B Cells / Maria J. Leandro. - Understanding B Cell Biology / Martin S. Naradikian, Jean L. Scholz, Michael A. Oropallo and Michael P. Cancro. - Pharmacological Effects and Mechanisms of Action of Agents Blocking B Cells / Ignacio Sanz. - Systemic Lupus Erythematosus: Direct B-Cell Blocking / Maria Ahijón Lana, Zozik Fattah, Susana Araujo Fernandez and David A. Isenberg. - Systemic Lupus Erythematosus: Indirect B-Cell Blocking / Pilar Brito-Zerón, Ma José Soto-Cárdenas, Soledad Retamozo and Xavier Bosch [and 2 others]. - B-Cell Targeted Therapies in Rheumatoid Arthritis / Stephan Blüml, Georg Stummvoll and Josef S. Smolen. - B-Cell Targeted Therapies in Primary Sjögren Syndrome / Pilar Brito-Zerón, Antoni Sisó-Almirall, Belchin Kostov, Xavier Bosch [and 2 others]. - Targeting B Cells in ANCA-Associated Vasculitides / Xavier Bosch and John H. Stone. - B-Cell Targeted Therapies in Systemic Sclerosis and Inflammatory Myopathies / Rohit Aggarwal, Vivek Nagaraja and Dinesh Khanna. - B-Cell Targeted Therapies in Cryoglobulinemia / Salvatore De Vita. - B-Cell Targeted Therapies in Autoimmune Cytopenias and Thrombosis / Bassem N. Matta, Rabih Nayfe, Ali T. Taher and Imad Uthman. - Targeting B Cells in Neurological Autoimmune Diseases / Maria Sepúlveda, Albert Saiz and Francesc Graus. - Targeting B Cells in Other Systemic Autoimmune Diseases / Xavier Bosch, Pilar Brito-Zerón, Munther A. Khamashta and Manuel Ramos-Casals. - Safety of B-Cell Targeted Therapies / Ian N. Bruce. - The Future Potential of Biosimilars Targeting B-Cells / Savino Sciascia, Dario Roccatello, Chary Lopez-Pedrera and Maria Jose' Cuadrado

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjogren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases

ISBN: 9783034807067

Standard No.: 10.1007/978-3-0348-0706-7 doi

Subjects--Topical Terms:
Enfermedades autoinmunes
Inmunología
Medicina interna

LC Class. No.: RC600 / .D78 2014 EB

Dewey Class. No.: 615