Cholesterol and Presynaptic Glutamate Transport in the Brain

Borisova, Tatiana

Cholesterol and Presynaptic Glutamate Transport in the Brain by Tatiana Borisova - New York Springer International Publishing 2013 - 1 recurso en línea (XVI, 75 p.) 32 il., 11 il. col. - SpringerBriefs in Neuroscience 12 2191-558X . - SpringerBriefs in Neuroscience 12 .

Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number ofÂrological and neurodegenerative disorders.Âpropriate levels of cholesterol are very important for the proper functioning of glutamate transport whileÂalanced levels ofÂlesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity.ÂÂ the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits.

9781461477594


Neurociencias

QP355.2 / B675 2013 EB