Multiplex Biomarker Techniques : Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification
Multiplex Biomarker Techniques : Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification
edited by Paul C. Guest
- 1st edition 2022
- 1 recurso en línea (XV, 417 páginas) 137 ilustraciones, 129 ilustraciones a color
- Methods in Molecular Biology 2511 1940-6029 .
Multiplex Technologies in COVID-19 Research, Diagnostics, and Prognostics: Battling the Pandemic -- Multivalent Vaccine Strategies in Battling the Emergence of COVID-19 Variants -- Challenges of Multiplex Assays for COVID-19 Research: A Machine Learning Perspective -- Multiplex Quantitative Polymerase Chain Reaction Diagnostic Test for SARS-CoV-2 and Influenza A/B Viruses -- Multiplex Quantitative Polymerase Chain Reaction Test to Identify SARS-CoV-2 Variants -- NIRVANA for Simultaneous Detection and Mutation Surveillance of SARS-CoV-2 and Co-Infections of Multiple Respiratory Viruses -- Quantitative Real-Time RT-PCR Systems to Detect SARS-CoV-2 -- Guidance for SARS-CoV-2 RNA-Based Molecular Assay Analytical Performance Evaluations -- A Rapid User-Friendly Lab-on-a-Chip Microarray Platform for Detection of SARS-CoV-2 Variants -- SARS-CoV-2 Host Immunogenetic Biomarkers -- FnCas9 Editor Linked Uniform Detection Assay for COVID-19 -- Mass Spectrometry Multiplexed Detection of SARS-CoV-2 -- Identification of Circulating Biomarkers of COVID-19 Using MALDI-TOF Mass Spectrometry -- Antibody-Based Affinity Capture Combined with LC-MS Analysis for Identification of COVID-19 Disease Serum Biomarkers -- Liquid Chromatography Mass Spectrometry Analysis of Peripheral Blood Mononuclear Cells from SARS-CoV-2 Infected Patients -- Assay of Fatty Acids and Their Role in the Prevention and Treatment of COVID-19 -- Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease -- Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases -- Detection of IgG Antibodies to SARS-CoV-2 and Neutralizing Capabilities Using the Luminex® xMAP® SARS-CoV-2 Multi-Antigen IgG Assay -- Multiplex Testing of the Effect of Statins on Disease Severity Risk in COVID-19 Cases -- Evaluating the Effects of Curcumin on the Cytokine Storm in COVID-19 Using a Chip-Based Multiplex Analysis -- COVID-19 Detection Using the NHS Lateral Flow Test Kit -- Evaluation Protocol for SARS-CoV-2 Serological Assays -- Measurement of Mitochondrial Respiration in Cryopreserved Human Peripheral Blood Mononuclear Cells (PBMCs) -- Multiplex Testing of Oxidative-Reductive Pathway in Patients with COVID-19 Disease -- Point-of-Care Device for Assessment of Blood Coagulation Status in COVID-19 Patients -- COVID-19 and the Assessment of Coenzyme Q10 -- Isolation and Cell Culture of Human Nasopharyngeal Cells: A Model for Testing Immune Response and Antiviral Treatment -- Machine Learning Approaches to Analyze MALDI-TOF Mass Spectrometry Protein Profiles -- A Deep Learning Approach to Identify Chest Computed Tomography Features for Prediction of SARS-CoV-2 Infection Outcomes -- Genomic Surveillance for Monitoring Variants of Concern: SARS-CoV-2 Delta, Omicron, and Beyond.
This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.
9781071623954
10.1007/978-1-0716-2395-4 doi
Marcadores biológicos--COVID-19
R853 .B54 / 2022 EB
Multiplex Technologies in COVID-19 Research, Diagnostics, and Prognostics: Battling the Pandemic -- Multivalent Vaccine Strategies in Battling the Emergence of COVID-19 Variants -- Challenges of Multiplex Assays for COVID-19 Research: A Machine Learning Perspective -- Multiplex Quantitative Polymerase Chain Reaction Diagnostic Test for SARS-CoV-2 and Influenza A/B Viruses -- Multiplex Quantitative Polymerase Chain Reaction Test to Identify SARS-CoV-2 Variants -- NIRVANA for Simultaneous Detection and Mutation Surveillance of SARS-CoV-2 and Co-Infections of Multiple Respiratory Viruses -- Quantitative Real-Time RT-PCR Systems to Detect SARS-CoV-2 -- Guidance for SARS-CoV-2 RNA-Based Molecular Assay Analytical Performance Evaluations -- A Rapid User-Friendly Lab-on-a-Chip Microarray Platform for Detection of SARS-CoV-2 Variants -- SARS-CoV-2 Host Immunogenetic Biomarkers -- FnCas9 Editor Linked Uniform Detection Assay for COVID-19 -- Mass Spectrometry Multiplexed Detection of SARS-CoV-2 -- Identification of Circulating Biomarkers of COVID-19 Using MALDI-TOF Mass Spectrometry -- Antibody-Based Affinity Capture Combined with LC-MS Analysis for Identification of COVID-19 Disease Serum Biomarkers -- Liquid Chromatography Mass Spectrometry Analysis of Peripheral Blood Mononuclear Cells from SARS-CoV-2 Infected Patients -- Assay of Fatty Acids and Their Role in the Prevention and Treatment of COVID-19 -- Lab-on-a-Chip Immunoassay for Prediction of Severe COVID-19 Disease -- Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases -- Detection of IgG Antibodies to SARS-CoV-2 and Neutralizing Capabilities Using the Luminex® xMAP® SARS-CoV-2 Multi-Antigen IgG Assay -- Multiplex Testing of the Effect of Statins on Disease Severity Risk in COVID-19 Cases -- Evaluating the Effects of Curcumin on the Cytokine Storm in COVID-19 Using a Chip-Based Multiplex Analysis -- COVID-19 Detection Using the NHS Lateral Flow Test Kit -- Evaluation Protocol for SARS-CoV-2 Serological Assays -- Measurement of Mitochondrial Respiration in Cryopreserved Human Peripheral Blood Mononuclear Cells (PBMCs) -- Multiplex Testing of Oxidative-Reductive Pathway in Patients with COVID-19 Disease -- Point-of-Care Device for Assessment of Blood Coagulation Status in COVID-19 Patients -- COVID-19 and the Assessment of Coenzyme Q10 -- Isolation and Cell Culture of Human Nasopharyngeal Cells: A Model for Testing Immune Response and Antiviral Treatment -- Machine Learning Approaches to Analyze MALDI-TOF Mass Spectrometry Protein Profiles -- A Deep Learning Approach to Identify Chest Computed Tomography Features for Prediction of SARS-CoV-2 Infection Outcomes -- Genomic Surveillance for Monitoring Variants of Concern: SARS-CoV-2 Delta, Omicron, and Beyond.
This detailed volume explores the application of multiplex biomarker methods in the critical area of COVID-19 research through state-of-the-art technologies in the fields of genomics, proteomics, transcriptomics, metabolomics, and imaging. The book features a series of protocols from labs across the globe employing multiplex molecular approaches, which can be applied to accelerate progress in the research of SARS-CoV-2 and other infectious illnesses. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and essential, Multiplex Biomarker Techniques: Methods and Applications for COVID-19 Disease Diagnosis and Risk Stratification serves as a vital resource for researchers in the areas of virology, metabolic diseases, respiratory disorders, as well as to clinical scientists, physicians, pharmacologists, and the healthcare services.
9781071623954
10.1007/978-1-0716-2395-4 doi
Marcadores biológicos--COVID-19
R853 .B54 / 2022 EB