Organic Cation Transporters in the Central Nervous System

Organic Cation Transporters in the Central Nervous System edited by Lynette C. Daws - First edition 2021 - 1 recurso en línea (XII, 328 páginas) 70 ilustraciones - Handbook of Experimental Pharmacology 266 1865-0325 Biomedical and Life Sciences (SpringerNature-11642) Biomedical and Life Sciences (R0) (SpringerNature-43708) .

General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.

Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, "General Overview of Organic Cation Transporters in Brain", of this book is available open access under a CC BY 4.0 license at link.springer.com.

9783030829841

10.1007/978-3-030-82984-1 doi


Ingeniería biomédica
Sistema nervioso central

R856 / 2021 EB